Whole Blood Cells
ACROBiosystems Human APP 2Vials
Amyloid precursor protein (APP) is a type I integral membrane protein ubiquitously expressed in many tissues and concentrated in the synapses of neurons. It has three predominant splice variants: APP695 APP751 and APP770. The majority of APP is cleaved at the plasma membrane by the α-secretase in the non-amyloidogenic pathway. The amyloidogenic pathway starts with β-secretase cleavage by BACE1 on the N-terminal part of the Aβ domain releasing sAPPβ from a membrane-anchored fragment named βCTF or C99 which is subsequently cleaved by γ-secretase to release Aβ.
ACROBiosystems Human LRRC15 2Vials
LRRC15 (Leucine-rich repeat-containing protein 15) is also known as LIB and hLib. LRRC15 is highly expressed in a variety of solid tumors. LRRC15 was expressed on stromal fibroblasts in many solid tumors (e.g. breast head and neck lung pancreatic) as well as directly on a subset of cancer cells of mesenchymal origin (e.g. sarcoma melanoma glioblastoma). LRRC15 expression was induced by TGFβ on activated fibroblasts (αSMA+) and on mesenchymal stem cells. These collective findings suggested LRRC15 as a novel CAF and mesenchymal marker with utility as a therapeutic target for the treatment of cancers with LRRC15-positive stromal desmoplasia or cancers of mesenchymal origin. ABBV-085 is a monomethyl auristatin E (MMAE)-containing antibody–drug conjugate (ADC) directed against LRRC15 and it demonstrated robust preclinical efficacy against LRRC15 stromal-positive/cancer-negative and LRRC15 cancer-positive models as a monotherapy or in combination with standard-of-care therapies.
ACROBiosystems Human LY6G6D 2Vials
LY6G6D belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 amino acids including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction.
ACROBiosystems Human Tau 2Vials
Tau is a microtubule-associated protein which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments which are involved in the pathogenesis of Alzheimers disease frontotemporal dementia and other tauopathies.
ACROBiosystems Human LILRB4 2Vials
Leukocyte immunoglobulin-like receptor subfamily B member 4 (LILRB4) is also known as CD85 antigen-like family member K (CD85K) Immunoglobulin-like transcript 3 (ILT-3) Leukocyte immunoglobulin-like receptor 5 (LIR-5) Monocyte inhibitory receptor HM18 which belongs to the leukocyte immunoglobulin-like receptor (LIR) family. LILRB4 / CD85K contains 2 Ig-like C2-type (immunoglobulin-like) domains. CD85K is detected in monocytes macrophages dendritic cells lung natural killer cells and B-cells. LILRB4 / CD85K is receptor for class I MHC antigens. CD85K recognizes a broad spectrum of HLA-A HLA-B HLA-C and HLA-G alleles involved in the down-regulation of the immune response and the development of tolerance. LILRB4 interferes with TNFRSF5-signaling and NF-kappa-B up-regulation and inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
ACROBiosystems Human CD19 2Vials
Chimeric antigen receptors (CARs) comprise interact domains of which target cancer cell expressed antigens and allow T cell to efficiently kill the cancer cell. FMC63 is an IgG2a mouse monoclonal antibody specific for CD19 which is a target for the immunotherapy of B lineage leukaemias and lymphomas. FMC63 scFv is the most commonly used ectodomain component of CD19-specific CARs. Our CAR-like cells apply the HEK293 cells for the expression of FMC63 which will be presented on the cell membrane. It mimics the real CAR-T cell reaction and it is used as positive control for Anti-CD19 scFv Antibody flow cytometry detection.
Kingfisher Biotech Inc Swine CXCL7 Recombinant Protein
The Swine CXCL7 yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Swine CXCL7 applications are for cell culture, ELISA standard, and Western Blot Control. Swine CXCL7 yeast-derived recombinant protein can be purchased in multiple sizes. Swine CXCL7 Specifications: (Molecular Weight: 8.6 kDa) (Amino Acid Sequence: AAKIEGRMAH VELRCLCLNT VSGIHPSNIQ SLEVIRAGAH CAKVEVIATL KNDKKICLDP EAPRIKKIVQ KIMEDGGSAA (80)) (Gene ID: 396870). For research use only. Made in the USA
Kingfisher Biotech Inc Canine CXCL7 Recombinant Protein
The Canine CXCL7 yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Canine CXCL7 applications are for cell culture, ELISA standard, and Western Blot Control. Canine CXCL7 yeast-derived recombinant protein can be purchased in multiple sizes. Canine CXCL7 Specifications: (Molecular Weight: 8.9 kDa) (Amino Acid Sequence: ETKSVDCERF LELRCMCTKT VSGIHPSNIQ NLEVLRAGPH CANVEVIAML KNGKRICLDP EAPKIKRIVQ KILESAERTA (80)) (Gene ID: 482196). For research use only. Made in the USA
Kingfisher Biotech Inc Bat CXCL10 Recombinant Protein
The Black/Large flying fox Bat CXCL10 yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Black/Large flying fox Bat CXCL10 applications are for cell culture, ELISA standard, and Western Blot Control. Black/Large flying fox Bat CXCL10 yeast-derived recombinant protein can be purchased in multiple sizes. Black/Large flying fox Bat CXCL10 Specifications: (Molecular Weight: 8.1 kDa) (Amino Acid Sequence: IPLFRTSRCV CIKISDQPVN LKSLEKLEVI PASQSCPQVE IIATMKKNGE KRCLNTKSKA VKNILKSISK ER (72)) (Gene ID: 102880650). For research use only. Made in the USA
Kingfisher Biotech Inc Ferret CXCL13 Recombinant Protein
The Ferret CXCL13 yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Ferret CXCL13 applications are for cell culture, ELISA standard, and Western Blot Control. Ferret CXCL13 yeast-derived recombinant protein can be purchased in multiple sizes. Ferret CXCL13 Specifications: (Molecular Weight: 9.9 kDa) (Amino Acid Sequence: VLEAYNTNLK CKCIQETSAF VPVNHIDKLQ VFPPGNGCPN KEVIVWKKNK SVVCLNPHSK WTQKLIKILQ RNAASTRPAP VLRRRMK (87)) (Gene ID: 101672630). For research use only. Made in the USA
Kingfisher Biotech Inc Rat CD27 Recombinant Protein
The Rat CD27 yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Rat CD27 applications are for cell culture, ELISA standard, and Western Blot Control. Rat CD27 yeast-derived recombinant protein can be purchased in multiple sizes. Rat CD27 Specifications: (Molecular Weight: 11.5 kDa) (Amino Acid Sequence: TPAPNNCPDR HYWIGAGLCC QMCGPGTFLV KHCDQDRAAA QCDPCIPGTS FSPDYHTRPH CESCRHCNSG FLIRNCTVTA NAECTCSKGW QCRDQECTEC DPPL (104)) (Gene ID: 116904587). For research use only. Made in the USA
Kingfisher Biotech Inc Ferret IL-6 Recombinant Protein
The Ferret IL-6 yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Ferret IL-6 applications are for cell culture, ELISA standard, and Western Blot Control. Ferret IL-6 yeast-derived recombinant protein can be purchased in multiple sizes. Ferret IL-6 Specifications: (Molecular Weight: 19.4 kDa) (Amino Acid Sequence: FPTPGPLGGD SKDDATSNRP PLTSADKMED FIRFILGKIS ALKKEMCEKY NKCEDSKEAL AENNLNLPKL AEEDKCFQSQ FNQETCLTRI TTGLQEFQIH LKYLEANYEG NKNNAHSVYI STKHLLQKLR PMNRVEVTTP DPTTDSSLQA LFKSQDKWLK HVTIHLILRS LEDFLQFSLR AIRIM (185)) (Gene ID: 101671465). For research use only. Made in the USA
Kingfisher Biotech Inc Canine IL-25 Recombinant Protein
The Canine IL-25 yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Canine IL-25 applications are for cell culture, ELISA standard, and Western Blot Control. Canine IL-25 yeast-derived recombinant protein can be purchased in multiple sizes. Canine IL-25 Specifications: (Molecular Weight: 17.7 kDa) (Amino Acid Sequence: LNFRIRKDCT HWPNCCPSKR QDPTHEWLKR DTVLKFPGET TSLTHHPESC KASEDGPLNS RSISPWKYEL DRDLNRLPQD LYHARCLCQH CVSLQTGSHM DPLGNSELLY HNQTVFYRRP CPGEQGAPDG YCLEQRLYRV SLACVCVRPR VMA). For research use only. Made in the USA
Kingfisher Biotech Inc Swine IL-16 Recombinant Protein
The Swine IL-16 yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Swine IL-16 applications are for cell culture, ELISA standard, and Western Blot Control. Swine IL-16 yeast-derived recombinant protein can be purchased in multiple sizes. Swine IL-16 Specifications: (Molecular Weight: 13.4 kDa) (Amino Acid Sequence: ASPDLNSSTD SAASVSVASD ISIDSTEATV CTVTLEKTSA GLGFSLEGGK GSLHGDKPLT INRIFRGAAS EQNETIQPGD EILHLAGTAV QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKGTTGAGDP (130)) (Gene ID: 396589). For research use only. Made in the USA
Kingfisher Biotech Inc Ferret IFN alpha Recombinant Protein
The Ferret IFN alpha yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Ferret IFN alpha applications are for cell culture, ELISA standard, and Western Blot Control. Ferret IFN alpha yeast-derived recombinant protein can be purchased in multiple sizes. Ferret IFN alpha Specifications: (Molecular Weight: 20.0 kDa) (Amino Acid Sequence: CDLPQDHGLL NWRALMLLRQ MRRVSTFSCL RDRNDFAFPQ EVFDGKPLQK AQAISVLHVT NQKTFHLFCT EASPAPWNTT LLEQLCSGLS EQMSHLAACP LQEAGVGETP LVNGDSILRN YFQRISLYLQ EKQYSHCAWE MVRAEIMKVF SSSTTLQERL RGKKQDLVQH GDDSH (175)) (Gene ID: 101686116). For research use only. Made in the USA